This is the second analytical report for Niue’s vital statistics based on civil registration data. This report covers birth, death and cause of death data collected in years 2012–2016, with comparisons made to previous years to show trends. Work for this project was supported by the Brisbane Accord Group of agencies under the leadership of the Pacific Community (SPC), Australian Bureau of Statistics (ABS), United Nations Childrens Fund (UNICEF), United Nations Economic and Social Commission for Asia and the Pacific (UNESCAP) and the World Health Organisation (WHO). The support from UNESCAP was made as part of the a project to strengthen National Capacity in Producing and Disseminating Vital Statistics, funded by the Bloomberg Philanthropies Data for Health Initiative.